Date of Award
Master of Science
Health and Sport Science
Randal K Buddington
Marie van der Merwe
Richard J Bloomer
Carbohydrate absorption may limit the benefits of carbohydrate ingestion during endurance exercise. Intestinal structural and functional adaptations were investigated in response to a vegan Daniel Fast diet (DF) or a Western Diet (WD), with or without endurance exercise training (DFE, DFS, WDE, WDS). Male Long-Evans rats (n = 28, aged 3-4 weeks) were assigned to the two diets and were either exercise trained by treadmill running or were sedentary for the 13 week intervention. Structural parameters significantly affected by diet (p <0.05) include villus height, crypt depths, intestine length and mass. Exercise significantly affected the percentage of mucosa in the proximal small intestine and several histological measurements (p <0.05). Functionally, WDE rats had higher proximal maltase activity (p = 0.04), but did not have higher rates of glucose uptake. A surprising finding is the intestine adapts to endurance exercise by reducing mass while maintaining carbohydrate digestion.
dissertation or thesis originally submitted to the local University of Memphis Electronic Theses & dissertation (ETD) Repository.
Daniels, Janice Lynn, "Intestinal Adaptations of Male Rats to Endurance Exercise and Diet" (2015). Electronic Theses and Dissertations. 1241.