Electronic Theses and Dissertations

Date

2024

Document Type

Thesis

Degree Name

Master of Science

Department

Nutrition

Committee Chair

Tracy Bruen

Committee Member

Karen Smith

Committee Member

Rachel Hill

Abstract

The treatment of pediatric acute lymphoblastic leukemia (ALL) often results in significant weight gain, which can lead to obesity and its associated health risks. This quality improvement project aimed to assess the use of bioelectrical impedance analysis (BIA) for the estimation of body composition and basal metabolic rate for the prevention of obesity in pediatric ALL patients. BIA was conducted on pediatric oncology patients at St. Jude Children’s Research Hospital. Retrospective BIA data was pulled at Cook Children’s Health Care Center. Participants (n=25) who met inclusion criteria (6-21 years of age and within weeks 20-50 of continuation in the TOTAL XVII protocol) had BIA conducted using either the InBody 770 or the Inbody 220 devices. Body fat percentages measured by the InBody device were compared to standard body fat percentages for the respective age and gender of participants. The calculated basal metabolic rate of the BIA device was compared to the estimated basal metabolic rate of predictive equations often incorporated into practice. All 25 participants were above 100% of their ideal body weight, ranging from 103%-219%. Of the 11 participants who had adjusted body weight calculated, all 11 were above 100% of their adjusted body weight, ranging from 117%-148%. On average the Schofield equation overestimated participants’ basal metabolic rate by 364.44 kcal. On average the WHO equation overestimated participants’ basal metabolic rate by 396.96 kcal. The outcomes of this quality improvement project provide evidence for the use of BIA in clinical practice and may aid in the development of targeted interventions to mitigate obesity and its associated health risks in pediatric ALL patients, ultimately enhancing their overall prognosis and quality of life.

Comments

Data is provided by the student.

Library Comment

Dissertation or thesis originally submitted to ProQuest.

Notes

Open Access

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