Electronic Theses and Dissertations

Date

2025

Document Type

Thesis

Degree Name

Master of Science

Department

Biomedical Engineering

Committee Chair

Carl Herickhoff

Committee Member

Amy Curry

Committee Member

Brent Hoffmeseister

Abstract

The Hybrid Angular Spectrum (HAS) method can be used to calculate ultrasound wave propagation through inhomogeneous tissue geometries, providing fast and accurate results. Volumetric matrices of sound speed and attenuation distributions and a planar incident pressure pattern are given as inputs, and the pressure wave propagation pattern is calculated plane-by-plane by alternating between the space domain and the spatial-frequency domain for each slice of the volume. This study aims to implement the HAS method in MATLAB to help reconstruct inhomogeneous 3D models of the temporal skull to identify ideal acoustic windows for transcranial ultrasound and inform custom array probe design. The HAS code accuracy was successfully determined by comparing the forward propagation through homogeneous water media with FieldII. CT scans of ex vivo human skulls were used to run simulations through sections of solid and porous temporal bone and to develop an iterative optimization process to converge from solid to porous.

Comments

Data is provided by the student.

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Notes

Open access.

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