Electronic Theses and Dissertations

Identifier

679

Date

2012

Date of Award

7-22-2012

Document Type

Thesis

Degree Name

Master of Science

Major

Health and Sport Science

Concentration

Exercise and Sport Science

Committee Chair

Murlasits Zsolt

Committee Member

Berman Jeffery

Committee Member

Schoech Steve

Abstract

Objective: This meta-analysis uses data from clincial studies of older men with low to low-normal concentrations of testosterone (T) that were treated with exogenous T to assess treatment efficacy on: lean body mass, fat mass, strength, and mobility. Methods: The data investigated are from published and referred journals. The Cohen's d was used to compute effect sizes from both pre-treatment and post-treatment scores. Results: The analysis revealed that T resulted in an overall significant (p = 0.037) improvement in physical characteristics and muscle function. After accounting for the variance, significance wa strengthened (p = 0.006) for the overall effect. When the dependent variables were considered independently, the largest contribution came from a decreases in fat mass (p = 0.003), followed by a non-significant trend (p = 0.06) for an increase in lean mass. After accounting for the variance for the dependent variables independently, lean mass (p = 0.0003), fat mass (p = 0.005), and strength (p = 0.02) were all found to be signifianct contributors. Conclusion: T administration can be considereda viable treatment for both the prevention and rehabilitation of decreased muscle mass and muscle strength seen in older men with low to low-normal T concentrations.

Comments

Data is provided by the student.

Library Comment

dissertation or thesis originally submitted to the local University of Memphis Electronic Theses & dissertation (ETD) Repository.

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