Electronic Theses and Dissertations





Document Type


Degree Name

Master of Science


Mechanical Engineering

Committee Chair

Gladius Lewis

Committee Member

Teong E Tan

Committee Member

Hsiang Hsi Lin


The literature on the interaction effects of explanatory variables on properties of injectable bone cements used in the vertebral augmentation procedures of vertebroplasty and ballon kyphoplasty is sparse. In the present work, response surface methodology was used to investigate the direct and interaction effects of variables on three properties of a poly (methyl methacrylate) bone cement (maximum exotherm temperature, residual monomer content (RMC), and degradability) and three properites of a calcium phosphate cement (CPC) (injectability, final setting time (F), and compressive strength). Some main findings were 1) interaction effects were statistically significant for some properties, such as F, but not for others, such as RMC; and 2) values of variables that led to optimum or minimum cement properties; for example, optimum injectability of a CPC (98%) could be attained using a cement with a poly(ethylene glycol) content of 20 wt/wt% and prepared using a powder-to-liquid ratio of 2.0 g mL-1.


Data is provided by the student.

Library Comment

Dissertation or thesis originally submitted to the local University of Memphis Electronic Theses & dissertation (ETD) Repository.