Date of Award
Master of Science
Hospital acquired infections are associated with increased mortality, morbidity, and costs. Medical Intensive Care Unit (MICU) patients have increased risk for HAI. Probiotics may be beneficial in reducing HAI. A retrospective chohort study was completed to determine the effect of food form probiotics in the prevention of HAI among MICU patients. Patients received probiotic containing 50 billion colony forming units daily for periods of 24 hours to 93 days. Infection rates three years prior, eight months during, and one year post probiotic implementation were comllected and compared with incidence of HAI in the same patient population. Significant differences in the incidence of central line associated bloodstream infection, ventilator associated pneumonia and Clostridium difficile associated diarrhea (CDAD), were indicated between control 1, the experimental group and control 2 using Chi square analysis. Food form probiotics were determined to be effective at reducing rates of CDAD in MICU patients.
Dissertation or thesis originally submitted to the local University of Memphis Electronic Theses & dissertation (ETD) Repository.
Nelson, Deidra Diane, "Probiotics Lactobacillus plantarum 299v and Bifidobacteria b1o7 in the Prevention of Hospital Associated Infections" (2014). Electronic Theses and Dissertations. 924.