Benzocrown derivatives as ionophores for alkali cations, III. Synthesis of ring‐cleaved analogues of benzocrown ethers a novel method for building up crown ether rings


Several ring‐cleaved analogues (9,11a,b) of bis(benzo‐15‐crown‐5)‐urethanes (1a, b) were prepared to study the change of complexation by electroanalytical methods. The syntheses of the title compounds (9,11a,b) were accomplished in two ways: starting from 4‐nitroveratrole (2) via intermediates 3–8 to give compound 9 and by alkaline hydrolytic cleavage of 4‐nitrobenzocrown ethers (10a,b) then by subsequent steps yielding 11a,b. Copyright © 1988 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim

Publication Title

Liebigs Annalen der Chemie