Electrospinning of nanofiber fibrinogen structures
Abstract
The first results of electrospinning fibrinogen nanofibers for use as a tissue-engineering scaffold, wound dressing, or hemostatic bandage are reported. Structures composed of fibrinogen fibers with an average diameter of 80-700 nm were electrospun from solutions composed of human or bovine fibrinogen fraction I dissolved in 1,1,1,3,3,3-hexafluoro-2-propanol and minimal essential medium (Earle's salts). In summary, the electrospinning process is a simple and efficient technique for the fabrication of 3D structures composed of fibrinogen fibers, as would be present in the physiologic environment.
Publication Title
Nano Letters
Recommended Citation
Wnek, G., Carr, M., Simpson, D., & Bowlin, G. (2003). Electrospinning of nanofiber fibrinogen structures. Nano Letters, 3 (2), 213-216. https://doi.org/10.1021/nl025866c
