Using measured intracavitary potentials to spatially map left-ventricular endocardial activation sequences


The objective of this study is to 1) calculate endocardial potentials from measured intracavitary potentials during the QRS complex via an inverse solution and 2) derive endocardial activation maps from the calculated endocardial waveforms. The aim of the study is to determine whether the derived activation sequences can provide the site of origin of ventricular arrhythmias. A cylindrical [51×11 mm] intracavitary probe with 57 evenly spaced unipolar electrodes on its surface and 49-58 subendocardial plunge electrodes were used to simultaneously record potentials within the left ventricular (LV) cavity and the LV endocardium, respectively. The results indicate that it is plausible to obtain the site of origin of ventricular arrhythmias from simultaneous intracavitary recordings. This is significant because utilization of multi-channel intracavitary probe recordings would reduce the time of potentially hazardous left ventricular exploration that is presently required to spatially map ventricular arrhythmias.

Publication Title

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

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