DNA-linked nanoparticle building blocks for programmable matter


One step at a time: DNA linkers were placed at defined locations and in defined 3D orientations on a colloidal nanoparticle. Because the implemented ligand-replacement strategy was carried out sequentially, DNA linkers maximally segregated, producing a nanoparticle with linkers at 90 or 180° angles (see picture). These building blocks should enable assembly of anisotropic nanostructures with precisely designed geometry and complex functionality. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Publication Title

Angewandte Chemie - International Edition