Alkaline hydrolysis of enantiomeric poly(lactide)s stereocomplex deposited on solid substrates


Poly(lactide)s stereocomplexes were hydrolyzed under concentrated alkaline conditions as an acceleration test. The complexes were prepared by the stepwise layer-by-layer assembly of poly(L-lactide) and poly(D-lactide) from their acetonitrile solutions on a solid substrate. The assembly and hydrolysis processes were quantitatively analyzed using a quartz crystal microbalance as the gold substrate. It was observed that the complex hydrolyzed faster than crystals of each constituent enantiomer.

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