Title

Alkylation of 5-cyanoimidazole-4-carboxamide

Abstract

Alkylation of 5-cyanoimidazole-4-carboxamide under alkaline conditions occurs with extremely high regioselectively at the nitrogen atom adjacent to the cyano group. The reaction is demonstrated to be useful for the synthesis of imidazo[1,5-a]pyrazines. © 1995.

Publication Title

Heterocycles

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