Benzocrown derivatives as ionophores for alkali cations, I synthesis of urethane‐ and urea‐linked mono‐ and bis‐crown ethers


New mono‐ and bis‐benzocrown ethers (5–28 and 29–48) with different substituents and connecting chains were prepared with the aim to develop novel alkali cation‐transport mediators for biological systems. The alkali cation selectivities of the title compounds were determined in ion‐selective membrane electrodes. Remarkable potassium selectivity was observed with several bis‐(benzo‐15‐crown‐5)urethanes. Copyright © 1988 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim

Publication Title

Liebigs Annalen der Chemie