Title

Improvement of surface adhesion of electrosprayed chitosan coatings to titanium substrates

Abstract

Statement of Purpose: Chitosan coatings have been attached to implant alloys surfaces via silane coupling reactions [1,2]. These coatings have shown potential to enhance implant integration into bone and to be used to locally deliver therapeutic such as antibiotics to prevent infection [2]. Electrospraying was recently investigated as a means to coat 3D titanium (Ti) surfaces with chitosan [3]. This study found that while electrospraying enabled precise control of the coating process, the deposited coatings had low bond strengths. Improving adhesion of electrosprayed chitosan coatings on Ti surfaces may be achieved by improving surface treatment and deposition of silane coupling agent on the Ti surfaces prior to electrospray coating. This work aimed to enhance silane deposition via enhancing hydroxide formation on Ti surfaces in order to improve adhesion of electrosprayed chitosan coatings.

Publication Title

Transactions of the Annual Meeting of the Society for Biomaterials and the Annual International Biomaterials Symposium

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