Synthesis of extended carbamate and urea linked thymidine dimers
Thymidine dimers with extended carbamate and urea linkages were synthesized. The length of the linker is expected to increase flexibility and improve duplex formation after incorporation into oligomer.
Nucleosides and Nucleotides
Ali, S., & Bridson, P. (1996). Synthesis of extended carbamate and urea linked thymidine dimers. Nucleosides and Nucleotides, 15 (9), 1531-1543. https://doi.org/10.1080/07328319608002452