Synthesis of the first C2-asymmetric phosphinine and its pyrylium precursor
The synthesis of the first C2 chiral phosphinine (phosphabenzene) and its pyrylium salt precursor is reported. The chiral phosphinine is derived from (+)-camphor, is a crystalline air-stable solid and is shown to effectively form complexes with metals. A preliminary result using the phosphinine as a ligand for asymmetric catalysis is reported and rationalized structurally. © 2009 Elsevier Ltd. All rights reserved.
Bell, J., Franken, A., & Garner, C. (2009). Synthesis of the first C2-asymmetric phosphinine and its pyrylium precursor. Tetrahedron, 65 (45), 9368-9372. https://doi.org/10.1016/j.tet.2009.08.085