The Exchange Kinetics of Macromolecules Adsorbed on a Solid Surface: A Theoretical Investigation


The exchange kinetics of macromolecules (e.g. polymers or proteins) desorbing from a solid surface is investigated using a theoretical model which accounts for both transport-controlled and detachment-controlled kinetics in a unified manner. In the transport-controlled regime, the decay has an effectively stretched-exponential behavior with an exponent that could vary anywhere from 0 to 1. The theoretical predictions agree well with the results from dynamic Monte Carlo simulations. The solution presented here will be valuable for interpreting exchange-kinetics experiments and can be used to obtain both the attachment rate and the detachment rate unambiguously. © 1995, American Chemical Society. All rights reserved.

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