Thermo-responsive gels: Biodegradable hydrogels from enantiomeric copolymers of poly(lactide) and poly(ethylene glycol)


Hydrogels responding to temperature changes are used for injectable biomaterials with many potential applications. Specifically, biocompatible hydrogels that can be safely injected without surgery and sustained/ disintegrated in a controlled manner are of interest. Poly(lactide), PLA, is the most studied and utilized bioresorbable polymer, and its block copolymers provide a great variety of structures and properties. Hydrogels utilizing stereocomplexation of the enantiomeric PLAs offer new polymer design and properties and expand their applications. © 2012 American Chemical Society.

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ACS Symposium Series