Altered copper metabolism in heterozygous tortoiseshell (Moto/+) female mice, Mus musculus


1. 1. The copper concentration of various tissues and excrement of normal (+/+) and heterozygous tortoiseshell (Moto/+) female mice were examined by atomic absorption spectrophotometry (AAS). 2. 2. The kidney, duodenum and spleen of Moto/+ female mice exhibited increased copper levels. 3. 3. A reduced copper content was detected in the plasma and erythrocytes of Moto/+ females. 4. 4. The feces and urine of Moto/+ females exhibited elevated copper concentrations. 5. 5. The other tissues examined (e.g. liver, lung) showed no significant copper level alterations. © 1982.

Publication Title

Comparative Biochemistry and Physiology -- Part A: Physiology