Copper localization in the duodenal mucosa of heterozygous tortoiseshell (Moto/+) female mice (Mus musculus)
The duodenal mucosa of normal (+/+) and heterozygous tortoiseshell (Moto/+) female mice was analysed by an ultrastructural histochemical copper localization technique. Copper was rarely detected along the duodenal microvilli of +/+ female mice. However, copper was localized on the surface of the brush border of the duodenal mucosa and within pinocytotic vesicles at the base of the microvilli of Moto/+ female mice. The mottled defect may involve a defective intestinal uptake of copper, as well as a faulty copper transport mechanism. © 1981, Cambridge University Press. All rights reserved.
Sheedlo, H., & Beck, M. (1981). Copper localization in the duodenal mucosa of heterozygous tortoiseshell (Moto/+) female mice (Mus musculus). Genetical Research, 38 (3), 333-336. https://doi.org/10.1017/S0016672300020656