Osteopontin (Eta-I) in cell-mediated immunity: Teaching an old dog new tricks
Previously regarded as an adhesive bone matrix protein, recent studies suggest that osteopontin (Eta-1) is also a novel RGD-containing cytokine that regulates early cell-mediated immunity. Proteins related to the extracellular matrix may function as important modulators of immune responses.
O'Regan, A., Nau, G., Chupp, G., & Berman, J. (2000). Osteopontin (Eta-I) in cell-mediated immunity: Teaching an old dog new tricks. Immunology Today, 21 (10), 475-478. https://doi.org/10.1016/S0167-5699(00)01715-1