Title

Osteopontin (Eta-I) in cell-mediated immunity: Teaching an old dog new tricks

Abstract

Previously regarded as an adhesive bone matrix protein, recent studies suggest that osteopontin (Eta-1) is also a novel RGD-containing cytokine that regulates early cell-mediated immunity. Proteins related to the extracellular matrix may function as important modulators of immune responses.

Publication Title

Immunology Today

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