The nature and identification of quantitative trait loci: A community's view

Authors

Oduola Abiola, King's College London
Joe M. Angel, Virginia Harris Cockrell Cancer Research Center at The University of Texas MD Anderson Cancer Center
Philip Avner, Institut Pasteur, Paris
Alexander A. Bachmanov, Monell Chemical Senses Center
John K. Belknap, Oregon Health & Science UniversityFollow
Beth Bennett, University of Colorado Boulder
Elizabeth P. Blankenhorn, Drexel University College of Medicine
David A. Blizard, Pennsylvania State University

Abstract

This white paper by eighty members of the Complex Trait Consortium presents a community's view on the approaches and statistical analyses that are needed for the identification of genetic loci that determine quantitative traits. Quantitative trait loci (QTLs) can be identified in several ways, but is there a definitive test of whether a candidate locus actually corresponds to a specific QTL?

Publication Title

Nature Reviews Genetics

Recommended Citation

Abiola, O., Angel, J., Avner, P., Bachmanov, A., Belknap, J., Bennett, B., Blankenhorn, E., & Blizard, D. (2003). The nature and identification of quantitative trait loci: A community's view. Nature Reviews Genetics, 4 (11), 911-916. https://doi.org/10.1038/nrg1206