Codon Bias Can Only Partially Explain Stop Signal Profile in Bacteria

Identifier

176

Author

Somanath Patrudu Pilla

Date

2010

Document Type

Thesis

Degree Name

Master of Science

Major

Bioinformatics

Committee Chair

Tit-Yee Wong

Committee Member

Ramin Homayouni

Committee Member

Donald Ourth

Committee Member

Lih-Yuan Deng

Abstract

The stop signals are nucleotide triplets, TAA, TAG, and TGA found on the first, second, and third reading frames of an open reading frame. The organization of bacterial stop signals may be a result of adaptation of individual species. A detail study of these signals and their relationship with their corresponding dicodons and dipeptides were analyzed in a broad range of bacterial genome. We classified each of these nine stop signals in a broad range of bacterial genomes. Results suggested that some of the stop signals are the result of codon bias due the chromosomal GC content. However, dicodon- and dipeptide- biases are also responsible for the formation of some stop signals.

Comments

Data is provided by the student.

Library Comment

Dissertation or thesis originally submitted to the local University of Memphis Electronic Theses & dissertation (ETD) Repository.

Recommended Citation

Pilla, Somanath Patrudu, "Codon Bias Can Only Partially Explain Stop Signal Profile in Bacteria" (2010). Electronic Theses and Dissertations. 129.
https://digitalcommons.memphis.edu/etd/129