Electronic Theses and Dissertations

Identifier

6111

Date

2017

Date of Award

12-6-2017

Document Type

Thesis

Degree Name

Master of Public Health

Major

Public Health

Concentration

Epidemiology

Committee Member

Vicky Nolan

Committee Member

Meredith Ray

Committee Member

Matthew Smeltzer

Abstract

The risk of infection associated with subcutaneous port (SQP) placement in patients with neutropenia remains unclear. We reviewed the rate of early infectious complications (<30 days) following SQP placement in pediatric oncology pateints with /without neutropenia (absolute neutrophil count (ANC) <500/mm3.Baseline characteristics and infectious complications were compared between groups using univariable and multivariable analysis.A total of 614 SQP were placed in 542 patients. Compared to non-neutropenic patients, those with neutropenia were more likely to have leukemia (94% vs 50%), pre-operative fever (22% vs 5%), pre-operative infection (19% vs 9%), and were younger (81 vs 109 months) (p values <0.01).After adjusting for fever and underlying-disease there was a non-significant association between neutropenia and early post operative infection (OR 2.41, 95% CI 0.82-7.18, p=0.116). Only pre-operative fever was a predictor of infection (OR 6.09, 95% CI 2.08-17.81, p=0.564).Neutropenia may not be a predictor of early postoperative infection following SQP placement.

Comments

Data is provided by the student.

Library Comment

dissertation or thesis originally submitted to the local University of Memphis Electronic Theses & dissertation (ETD) Repository.

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