Electronic Theses and Dissertations

Identifier

802

Date

2013

Document Type

Thesis

Degree Name

Master of Science

Major

Health and Sport Science

Concentration

Exercise and Sport Science

Committee Chair

Richard J. Bloomer

Committee Member

Randal K. Buddington

Committee Member

Zsolt Murlasits

Abstract

While RONS are produced as part of normal metabolism, excess production can occur in response to stressors, such as physical exercise and ingestion of excess nutrients (e.g., saturated fat). Over time this may lead to an up-regulation in antioxidant enzyme activity, in an attempt to protect cells. The purpose of this investigation was to determine if an increase in antioxidant enzyme activity is observed following repeatedingestion of high fat meals. Sixteen healthy men consumed10 high fat milkshakes over a 3+ weekperiod. Blood was taken from subjects on the firstday of each week (before andfor 4 hours after milkshake ingestion) and analyzed for oxidative stress biomarkers. Repeated high-fat feeding didnot result in anyup-regulation in antioxidant enzymatic activity or attenuation in oxidative stress. Thesedata indicate that the RONS production associated with repeated consumption of high-fat meals does not induce an adaptive response within the blood antioxidant defense system.

Comments

Data is provided by the student.

Library Comment

Dissertation or thesis originally submitted to the local University of Memphis Electronic Theses & dissertation (ETD) Repository.

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