Left ventricular noncompaction in a family with lamin A/C gene mutation

Authors

• John J. Parent, Cincinnati Children's Hospital Medical Center
• Jeffrey A. Towbin, Cincinnati Children's Hospital Medical Center
• John L. Jefferies, Cincinnati Children's Hospital Medical Center

Abstract

Left ventricular noncompaction is a rare type of cardiomyopathy, the genetics of which are poorly understood to date. Lamin A/C gene mutations have been associated with dilated cardiomyopathy and diseases of the conduction system, but rarely in left ventricular noncompaction cardiomyopathy. This report describes the cases of 4 family members with a lamin A /C gene mutation, 3 of whom had phenotypic expression of left ventricular noncompaction.

Publication Title

Texas Heart Institute Journal

Recommended Citation

Parent, J., Towbin, J., & Jefferies, J. (2015). Left ventricular noncompaction in a family with lamin A/C gene mutation. Texas Heart Institute Journal, 42 (1), 73-76. https://doi.org/10.14503/THIJ-13-3843