Randomized clinical trial of therapeutic music video intervention for resilience outcomes in adolescents/young adults undergoing hematopoietic stem cell transplant: A report from the Children's Oncology Group

Authors

• Sheri L. Robb, IU School of Nursing
• Debra S. Burns, Indiana University-Purdue University Indianapolis
• Kristin A. Stegenga, Children's Mercy Hospitals and Clinics
• Paul R. Haut, Indiana University School of Medicine
• Patrick O. Monahan, Indiana University School of Medicine
• Jane Meza, University of Nebraska Medical Center
• Timothy E. Stump, Indiana University School of Medicine
• Brooke O. Cherven, Emory University
• Sharron L. Docherty, Duke University
• Verna L. Hendricks-Ferguson, St. Louis University School of Nursing
• Eileen K. Kintner, The University of Texas at Austin
• Ann E. Haight, Emory University
• Donna A. Wall, CancerCare Manitoba
• Joan E. Haase, IU School of Nursing

Abstract

BACKGROUND To reduce the risk of adjustment problems associated with hematopoietic stem cell transplant (HSCT) for adolescents/young adults (AYAs), we examined efficacy of a therapeutic music video (TMV) intervention delivered during the acute phase of HSCT to: 1) increase protective factors of spiritual perspective, social integration, family environment, courageous coping, and hope-derived meaning; 2) decrease risk factors of illness-related distress and defensive coping; and 3) increase outcomes of self-transcendence and resilience. METHODS This was a multisite randomized, controlled trial (COG-ANUR0631) conducted at 8 Children's Oncology Group sites involving 113 AYAs aged 11-24 years undergoing myeloablative HSCT. Participants, randomized to the TMV or low-dose control (audiobooks) group, completed 6 sessions over 3 weeks with a board-certified music therapist. Variables were based on Haase's Resilience in Illness Model (RIM). Participants completed measures related to latent variables of illness-related distress, social integration, spiritual perspective, family environment, coping, hope-derived meaning, and resilience at baseline (T1), postintervention (T2), and 100 days posttransplant (T3). RESULTS At T2, the TMV group reported significantly better courageous coping (Effect Size [ES], 0.505; P =.030). At T3, the TMV group reported significantly better social integration (ES, 0.543; P =.028) and family environment (ES, 0.663; P =.008), as well as moderate nonsignificant effect sizes for spiritual perspective (ES, 0.450; P =.071) and self-transcendence (ES, 0.424; P =.088). CONCLUSIONS The TMV intervention improves positive health outcomes of courageous coping, social integration, and family environment during a high-risk cancer treatment. We recommend the TMV be examined in a broader population of AYAs with high-risk cancers. Cancer 2014;120:909-917. © 2013 American Cancer Society. Adolescents/young adults undergoing stem cell transplant for cancer who received a therapeutic music video intervention demonstrated significant posttransplant improvement in resilience-related outcomes of courageous coping, family support/communication, and social support from friends and health care providers. © 2013 American Cancer Society.

Publication Title

Cancer

Recommended Citation

Robb, S., Burns, D., Stegenga, K., Haut, P., Monahan, P., Meza, J., Stump, T., Cherven, B., Docherty, S., Hendricks-Ferguson, V., Kintner, E., Haight, A., Wall, D., & Haase, J. (2014). Randomized clinical trial of therapeutic music video intervention for resilience outcomes in adolescents/young adults undergoing hematopoietic stem cell transplant: A report from the Children's Oncology Group. Cancer, 120 (6), 909-917. https://doi.org/10.1002/cncr.28355