The effect of long-term, high-volume aerobic exercise training on postprandial lipemia and oxidative stress
Abstract
Aims: We have previously found no effect of moderate-volume aerobic exercise training (∼3 hrs·wk-1) on postprandial oxidative stress. It is possible that a higher volume of exercise is needed to impact postprandial oxidative stress in young, otherwise healthy individuals. Our purpose was to compare blood triglycerides (TAGs) and oxidative stress biomarkers in 10 healthy untrained and 10 healthy highly aerobically trained (eg, ≥ 40 miles running·wk-1 or ≥ 150 miles cycling·wk-1) men and women following ingestion of a lipid meal. Methods: Blood samples were collected before (in a 10-hour fasted state), and 1, 2, 4, and 6 hours after ingestion of a lipid load (heavy whipping cream at 1 g·kg-1). Blood samples were analyzed for TAGs, malondialdehyde (MDA), hydrogen peroxide (H2O2), and nitrate/nitrite (NOx). Results: No training status or interaction effects were noted for TAGs, MDA, H2O2, or NOx (P > 0.05). However, a time effect was noted for TAGs (P = 0.01), with values higher at 2 hours (67 ± 6 mg·dL-1) compared with premeal (41 ± 6 mg·dL-1). A time effect was also noted for H2O 2 (P = 0.0001), with values higher at 2 hours (24 ± 3 μmol·L-1), 4 hours (23 ± 3 μmol·L -1), and 6 hours (21 ± 3 μmol·L-1) compared with premeal (7 ± 2 μmol·L-1). The time effect for MDA approached significance (P = 0.07), with values peaking at 4 hours post-meal (1.59 ± 0.16 μmol·L-1) compared with premeal (0.99 ± 0.15 μmol·L-1). Conclusion: These data indicate that aerobic exercise training (even when performed at a relatively high volume) does not attenuate postprandial lipemia or oxidative stress as compared with no exercise when healthy men and women consume a lipid load in the form of heavy whipping cream. Fasting TAG values may be most important in this regard. It is possible that long-term exercise may be capable of att enuating postprandial lipemia or oxidative stress in older individuals, those with chronic disease, or those with elevated fasting TAG values. Future work is needed to confirm these hypotheses. © The Physician and Sportsmedicine.
Publication Title
Physician and Sportsmedicine
Recommended Citation
Bloomer, R., Fisher-Wellman, K., & Bell, H. (2010). The effect of long-term, high-volume aerobic exercise training on postprandial lipemia and oxidative stress. Physician and Sportsmedicine, 38 (1), 64-71. https://doi.org/10.3810/psm.2010.04.1763
