A new spin on scaffolds

Abstract

The properties and applications of nanostructured scaffolds developed using the electrospinnig process were discussed. These nanostructured scaffolds mimic the native extracellular matrix (ECM). Upon electrospinning, the native proteins display not only the structural aspects of the ECM but also the ultrastructure, that is the composition of the building blocks within the fibers. In terms of physiological acceptance, nanofibrous scaffolds regardless of composition, induce a reduced inflammatory response and in the case of native proteins, a minimal response was observed.

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Materials Today

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