Functional nanofibers for tissue engineering applications

Abstract

Tissue engineering aims to restore function or replace damaged tissue through biological principles and engineering. Electrospinning is a scaffold fabrication technique that produces continuous nanofiber meshes that mimic the extracellular matrix (ECM) of native tissue. This chapter briefly introduces various tissues and their respective ECM structure and composition. It then discusses the use of electrospun scaffolds intended for tissue engineering of each tissue, specifically focusing on cell response/growth to various electrospun nanofibers (natural/synthetic polymers, composites, incorporation of biological factors, effects of surface modifications, etc.). © 2012 Woodhead Publishing Limited All rights reserved.

Publication Title

Functional Nanofibers and their Applications

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