Intracranial catheter for integrated 3D ultrasound imaging & hyperthermia: Feasibility study
Abstract
In this study, we investigated the feasibility of an intracranial catheter transducer capable of real-time 3D (RT3D) imaging and ultrasound hyperthermia, for application in the visualization and treatment of tumors in the brain. We designed and constructed a 12 Fr, integrated matrix and linear array catheter transducer prototype for combined RT3D imaging and heating capability. This dual-mode catheter incorporated 153 matrix array elements and 11 linear array elements, on a 0.2 mm pitch, with a total aperture size of 8.4 mm × 2.3 mm. This array achieved a 3.5°C in vitro temperature rise at a 2 cm focal distance in tissue-mimicking material. The dual-mode catheter prototype was compared with a Siemens 10 Fr AcuNav™ catheter as a gold standard in experiments assessing image quality and therapeutic potential, and both probes were used in a canine brain model to image anatomical structures and color Doppler blood flow and to attempt in vivo heating. © 2009 American Institute of physics.
Publication Title
AIP Conference Proceedings
Recommended Citation
Herickhoff, C., Light, E., Bing, K., Mukundan, S., Grant, G., Wolf, P., Dixon-Tulloch, E., Shih, T., Hsu, S., & Smith, S. (2009). Intracranial catheter for integrated 3D ultrasound imaging & hyperthermia: Feasibility study. AIP Conference Proceedings, 1113, 342-346. https://doi.org/10.1063/1.3131444
