Post-implantation evidence of persistence/origin of electrostatically seeded endothelial cells

Abstract

The purpose of this study was to provide evidence of the persistence of electrostatically seeded endothelial cells (EC) lining an expanded polytetrafluoroethylene (e-PTFE) graft after implantation in a canine femoral artery bypass model. This study also confirmed the origin (seeding inoculum) of the ECs which initiate neointimal formation. The evidence was obtained by visualizing a PKH26 (fluorescent) label incorporated in the EC membranes.

Publication Title

Annals of Biomedical Engineering

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