Wireless simultaneous stimulation-and-recording device to train cortical circuits in somatosensory cortex
Abstract
We describe for the first time the design, implementation, and testing of a telemetry controlled simultaneous stimulation and recording device (SRD) to deliver chronic intercortical microstimulation (ICMS) to physiologically identified sites in rat somatosensory cortex (SI) and test hypotheses that chronic ICMS strengthens interhemispheric pathways and leads to functional reorganization in the enhanced cortex. The SRD is a custom embedded device that uses the Cypress Semiconductor's programmable system on a chip (PSoC) that is remotely controlled via Bluetooth. The SRC can record single or multiunit responses from any two of 12 available inputs at 1-15 ksps per channel and simultaneously deliver stimulus pulses (0-255 μA; 10 V compliance) to two user selectable electrodes using monophasic, biphasic, or pseudophasic stimulation waveforms (duration: 0-5 ms, inter-phase interval: 0-5 ms, frequency: 0.1-5 s, delay: 0-10 ms). The SRD was bench tested and validated in vivo in a rat animal model.
Publication Title
2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014
Recommended Citation
Ramshur, J., De Jongh Curry, A., & Waters, R. (2014). Wireless simultaneous stimulation-and-recording device to train cortical circuits in somatosensory cortex. 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, 426-429. https://doi.org/10.1109/EMBC.2014.6943619
