Ceric ammonium nitrate catalyzed oxidation of sulfides to sulfoxides

Abstract

Oxidation of sulfides to sulfoxides with a catalytic amount of ceric ammonium nitrate (CAN) reagent supported on silica gel has been achieved. Stoichiometric sodium bromate is utilized as the primary oxidant to continue the catalytic cycle involving CAN. Solid-supported CAN reagent allowed us to avoid using aqueous reaction media generally employed in CAN-promoted reactions. This heterogeneous CAN/NaBrO3 reagent has simplified the reaction work-up and product isolation, produced higher product yields, and shortened reaction times compared to reactions with homogeneous CAN reagents employing aqueous media. © Georg Thieme Verlag Stuttgart.

Publication Title

Synthesis

Link to Full Text

Share

COinS