Domino ligand-free copper-catalyzed synthesis of polysubstituted indoles
Abstract
The synthesis of polysubstituted indoles is described by the domino reaction of 2-haloanilines and 1,3-dicarbonyl compounds, 1,3-diketones, β-keto esters and β-keto amides, using copper catalysis under ligand-free conditions. The protocol provides a simple, general and atom economical process for the synthesis of substituted indoles at moderate temperature. © Georg Thieme Verlag Stuttgart - New York.
Publication Title
Synlett
Recommended Citation
Ali, M., & Punniyamurthy, T. (2011). Domino ligand-free copper-catalyzed synthesis of polysubstituted indoles. Synlett (5), 623-626. https://doi.org/10.1055/s-0030-1259548
COinS
