Independent sets of DNA oligonucleotides for nanotechnology applications

Authors

Weixia Yu, University of California, Los Angeles
Ju Seok Lee, University of Arkansas
Cole Johnson, Washington University in St. Louis
Jin Woo Kim, University of ArkansasFollow
Russell Deaton, University of California, Los AngelesFollow

Abstract

Independent sets of DNA oligonucleotides, which only bind with their WatsonCrick complements, have potential use in self-assembly of nanostructures, since they minimize errors and inefficiency from unwanted binding. A software tool implemented a thermodynamic model for DNA duplex formation and was used to generate large independent sets of DNA oligonucleotides. The principle of the approach was experimentally verified on a sample set of oligonucleotides. © 2006 IEEE.

Publication Title

IEEE Transactions on Nanobioscience

Recommended Citation

Yu, W., Lee, J., Johnson, C., Kim, J., & Deaton, R. (2010). Independent sets of DNA oligonucleotides for nanotechnology applications. IEEE Transactions on Nanobioscience (1), 38-43. https://doi.org/10.1109/TNB.2009.2035446