Oxidation of thiols to disulfides with molecular bromine on hydrated silica gel support

Abstract

Results of oxidation of thiols to disulfides with molecular bromine on silica gel solid support are reported. The procedure utilizes organic media and does not require a base to neutralize HBr by-products to suppress acid promoted side reactions. Utilization of silica gel support simplifies work up and product isolation. © 2002 Elsevier Science Ltd. All rights reserved.

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