Synthesis, crystal structure and antimicrobial studies of chlorido(dimethylsulfoxide-κS)(pyrrolidinedithiocarbamato- κ²S,S^/)platinum(II)

Authors

Anvarhusein A. Isab, King Fahd University of Petroleum and Minerals
Muhammad Akhtar Javed Ali, University of Engineering and Technology, Lahore
Shahzad Sharif, Government College University Lahore
Islam Ullah Khan, Government College University Lahore
Sung Kwon Kang, Chungnam National University
Tanzeel Khalid, KRL Hospital
Muhammad Saleem, Jubail University College
Saeed Ahmad, University of Engineering and Technology, Lahore

Abstract

Platinum(II) complexes, [Pt(PDTC)(H2O)Cl] and [Pt(PDTC)(DMSO)Cl] (1) (PDTC = pyrrolidinedithiocarbamate) have been prepared and characterized by IR, NMR and X-ray crystallographic methods. In the crystal structure of 1 the central platinum atom is coordinated to two sulfur atoms of PDTC, one sulfur atom of DMSO and one chloride ion adopting a square planar geometry with the average cis and trans bond angles of 90.00° and 171.62° respectively. The 1H and 13C NMR spectral data indicate the coordination of both PDTC and DMSO to platinum(II). The title complex was screened for antimicrobial effects and the results show that it exhibits significant activity against gram-negative bacteria (E. coli, P. aeruginosa), while the activities are moderate against molds (A. niger, P. citrinum) and yeasts (C. albicans, S. serevisaiae). © 2011 Elsevier B.V. All rights reserved.

Publication Title

Inorganic Chemistry Communications

Recommended Citation

Isab, A., Ali, M., Sharif, S., Khan, I., Kang, S., Khalid, T., Saleem, M., & Ahmad, S. (2011). Synthesis, crystal structure and antimicrobial studies of chlorido(dimethylsulfoxide-κS)(pyrrolidinedithiocarbamato- κ²S,S^/)platinum(II). Inorganic Chemistry Communications (12), 1962-1965. https://doi.org/10.1016/j.inoche.2011.09.021