Alkylation of 5-cyanoimidazole-4-carboxamide

Authors

Peter K. Bridson, University of MemphisFollow
Rekha V. Iyengar, University of Memphis

Abstract

Alkylation of 5-cyanoimidazole-4-carboxamide under alkaline conditions occurs with extremely high regioselectively at the nitrogen atom adjacent to the cyano group. The reaction is demonstrated to be useful for the synthesis of imidazo[1,5-a]pyrazines. © 1995.

Publication Title

Heterocycles

Recommended Citation

Bridson, P., & Iyengar, R. (1995). Alkylation of 5-cyanoimidazole-4-carboxamide. Heterocycles, 41 (6), 1271-1274. https://doi.org/10.3987/com-95-7054