Clinical and phenotypic diversity of T cell lymphomas
Abstract
Forty-one cases of T cell lymphoma were identified on the basis of morphology and the expression of two or more T cell antigens with an absence of B cell markers. Mycosis fungoides and lymphoblastic lymphoma were excluded. Marked clinical, morphological, and immunologic diversity was observed. Cutaneous lymphoma was found in ~50% of the patient group, and 27% had a prior history of dermatologic or immunologic disease. No correlations among immunologic and morphologic phenotypes and clinical course were apparent. Survival data was comparable to that of a concurrent group of non-T cell lymphoma patients studied at this institution, suggesting that, contrary to previous reports, T cell lymphoma may not necessarily confer a more unfavorable prognosis. Prospective studied using uniform treatments are necessary to address the clinical signficance of the T cell phenotype definitively, independent of established histologic and clinical features.
Publication Title
Blood
Recommended Citation
Horning, S., Weiss, L., Crabtree, G., & Warnke, R. (1986). Clinical and phenotypic diversity of T cell lymphomas. Blood, 67 (6), 1578-1582. https://doi.org/10.1182/blood.v67.6.1578.1578
