Menthyldichlorophosphate: A chiral derivatizing agent for symmetrical diols

Abstract

Menthyldichlorophosphate reacts readily with a variety of C2-chiral and meso diols to yield phosphate esters that exhibit useful diastereomeric differences in the 31P NMR spectra. Meso and d,l diols are easily differentiated with this reagent.

Publication Title

Tetrahedron Letters

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