Phase behavior of pure lipid bilayers with mismatch interactions
Abstract
Recently Corvera, Laradji, and Zuckermann (unpublished) showed that the multistate lattice model due to Pink, Green, and Chapman [Biochemistry 20, 6692 (1981)] with parameters obtained from fitting to thermodynamic data for saturated phospholipid bilayers does not exhibit a phase transition but could instead be described in terms of short-range fluctuations close to a critical point. We have extended the Pink-Green-Chapman model by including hydrophobic mismatch interactions between the lipid acyl-chain conformational states. We used Monte Carlo techniques to examine the phase behavior of the extended model and found that it exhibits first-order phase transitions above a critical value of the mismatch parameter. The results are discussed in relation to previous theoretical work as well as experimental measurements on lipid bilayers. © 1992 The American Physical Society.
Publication Title
Physical Review A
Recommended Citation
Zhang, Z., Laradji, M., Guo, H., Mouritsen, O., & Zuckermann, M. (1992). Phase behavior of pure lipid bilayers with mismatch interactions. Physical Review A, 45 (10), 7560-7567. https://doi.org/10.1103/PhysRevA.45.7560
