Influence of aerobic exercise training on postprandial oxidative stress

Abstract

Exercise training is known to impart beneficial effects on glucose and lipid processing, in addition to increasing antioxidant defense. These adaptations may serve to minimize the oxidative stress which typically occurs post feeding. Purpose: To determine the effects of aerobic exercise training on postprandial oxidative stress biomarkers. Methods: Twenty previously sedentary subjects were randomly assigned to an eight week aerobic exercise training intervention (3 sessions/week; 30-45 minutes/session; n=10; age: 36±3yrs; fasting blood glucose: 106±4mg·dL-1; BMI: 34±2 kg·m-2) or a usual care control group (n=10; age: 31±2yrs; fasting blood glucose: 101±4mg·dL-1; BMI: 33±2 kg·m-2). Before and within two days following the intervention, subjects consumed a lipid/carbohydrate rich test meal. Blood samples were collected pre meal (fasted), and at 1, 2, 4, and 6 hours post meal and assayed for xanthine oxidase activity (XO), hydrogen peroxide (H2O2), malondialdehyde (MDA), triglycerides (TAG), and glucose. Area under the curve (AUC) was calculated for each variable, both pre and post intervention. Results: Exercise training had no effect on decreasing the AUC for any variable (p>0.05). All variables followed an expected pattern over the 6 hour postprandial period, with the peak response in most variables noted at 4-6 hours post meal. Conclusion: Aerobic exercise training performed at the frequency, duration and intensity in the present study has no effect on postprandial TAG or oxidative stress biomarkers within a sample of previously sedentary subjects. © 2012 Nova Science Publishers, Inc.

Publication Title

Handbook on Oxidative Stress New Research

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