Electronic Theses and Dissertations
Identifier
6100
Date
2017
Document Type
Thesis
Degree Name
Master of Science
Major
Clinical Nutrition
Committee Chair
Ruth Williams-Hooker
Committee Member
Melissa Puppa
Abstract
Background: Inborn errors of protein metabolism (IEPM) cause the build-up of certain amino acid by products in the body. The treatment for IEPMs is a metabolic formula that eliminates the amino acid that the person with the IEPM cannot metabolize. The purpose of this study was to determine if patients with an IEPM consuming metabolic formula were taller than healthy individuals. Methods: Analysis of height, weight, calories, protein, iron, and vitamin B12 were compared to height using a regression correlation. Proper growth was determined if the height-for-age curve was greater than the 50th percentile. Results: The mean height percentile was 41.23 (p= 0.1885), indicating that the participants heights were not different from the healthy population. The protein intake compared to the RDA was significantly different (p<+0.0001). The mean protein intake was 15.89 and intakes were significantly higher than the RDA. Calories, iron, zinc, and vitamin B-12 intake was compared to the average height percentile and were not correlated to height. Discussion and Conclusions: There was no significant difference overall in nutrient intake to height percentile, with protein intake being an exception. The protein intake was inversely correlated to height. Although this seems contrary to what one would think, further investigation is needed.
Library Comment
Dissertation or thesis originally submitted to the local University of Memphis Electronic Theses & dissertation (ETD) Repository.
Recommended Citation
West, Emily Ann, "The Effects of Metabolic Formula on Growth Outcomes in Patients with Inborn Errors of Protein Metabolism" (2017). Electronic Theses and Dissertations. 1778.
https://digitalcommons.memphis.edu/etd/1778
Comments
Data is provided by the student.