Efficient copper-catalyzed N-arylation of amides and imidazoles with aryl iodides

Abstract

The C-N cross-coupling of amides and imidazoles with aryl iodides is described using CuI in tetrabutylammonium bromide (TBAB) under ligand-free conditions. The reaction is simple, general, and efficient affording the C-N cross-coupled products in shorter time and in high yield. © Georg Thieme Verlag Stuttgart • New York.

Publication Title

Synthesis

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