Finite element analysis of a model of simulated vertebral cement augmentation: Influence of the representation of the shape of the cement domain on biomechanical parameters

Abstract

Vertebral cement augmentation is rapidly becoming the modality of choice for treating patients who are experiencing severe and persistent pain because of osteoporosis-induced vertebral compression fracture(s). The resulting cement domain (the part of the vertebral body (VB) filled with the cement) has an irregular or complicated shape. In literature reports of finite element analysis (FEA) of models of simulated vertebral cement augmentation, a variety of representations of the shape of the cement domain have been used. In the literature, only very limited attention has been given to the issue of the influence of cement domain shape representation on biomechanical parameters for a given combination of model and loading. This issue is the subject of the present work, with the model being of the L1-L3 motion segments. Augmentation of an unfractured L2 (prophylactic augmentation) was simulated, three cement domain shapes were considered namely, solid cylinder, with rounded edges; two prolate spheroids; and oblate spheroid and the applied loading comprised a simultaneous application of a uniform compressive pressure of 0.53 MPa (equivalent to an 800-N compression load) and a counter-clockwise-acting axial rotation moment of 1 Nm to the superior surface of L1. It was found that (1) while the cement domain shape representation has a marked influence on the mean von Mises stress (σAVM), the maximum von Mises stress (σMVM), and the strain energy density (MSED) distribution in the cement domain, its influence on each of these parameters in each of the biological tissues in the model as well as on the total segmental range of motion is minimal and (2) for σAVM and σMVM, the lowest value of each of these parameters was obtained when the oblate spheroid model was used. From both clinical and computational perspectives, these findings are significant. For example, the latter finding suggests that there is scope for researching the combination of key process variables used, such as the cement chemistry, the cement delivery system, and the augmentation technique/approach, that would ensure that the final cement domain shape in cement-augmented VBs of patients be oblate spheroid on a consistent and predictable basis. © 2010 World Scientific Publishing Company.

Publication Title

Journal of Mechanics in Medicine and Biology

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